Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0314529
PubChem CID
Molecular Formula
C13H10N2O2
Molecular Weight
226.235 g/mol
Synonyms/Alias
[beta-CCM; 69954-48-9; beta-Carboline-3-carboxylic acid methyl ester; Methyl beta-carboline-3-carboxylate; methyl 9H-pyrido[3;4-b]indole-3-carboxylate; 3-Carbomethoxy-beta-carboline; CHEMBL268191; CHE...
InChI Key
UKHFPVCOXBJPIN-UHFFFAOYSA-N
InChI
InChI=1S/C13H10N2O2/c1-17-13(16)11-6-9-8-4-2-3-5-10(8)15-12(9)7-14-11/h2-7,15H,1H3
IUPAC Name
methyl 9H-pyrido[3,4-b]indole-3-carboxylate
CAS Number
74214-62-3

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

27 29 0 0 0 0 0 0 0 0999 V2000
5.6137 0.6118 0.3202 C 0 0 0 0 0 0 0 0 0 0 0 0
4.2621 0.8598 -0.0476 O 0 0 0 0 0 0 0 0 0 0 0 0
3.2050 0.046...

Experimental Data

Activity Data

Target Ion Channel
Gamma-aminobutyric acid receptor subunit alpha-4beta-3/gamma-2s
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
N/A (Not available)
EC50
N/A (Not available)
Ki
Ki: 640 nM
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
Not specified
Temperature
4 °C
Test Method
Binding assay
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)

Binding Information

Binding Site
Extracellular domain
Binding Site Residue
Benzodiazepine binding site

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
17
Rotatable Bonds
1
logP
2.5027
Complexity
64.9392
TPSA (Ų)
54.98
H-Bond Donors
1
H-Bond Acceptors
3
Ring Count
3
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